Document Detail


Reticulocytes in athletes: Longitudinal aspects and the influence of long- and short-term exercise.
MedLine Citation:
PMID:  20886465     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Reticulocytes (Ret) are a key variable in the emerging concept of the athlete's biological passport and the longitudinal monitoring of biological parameters in the field of anti-doping. In this context, knowledge on the variability of Ret in athletes and the influence of exercise is necessary. The aim of the present study was to evaluate longitudinal variation in Ret and the influence of short- and long-term exercise.Ret% in 793 samples of 238 athletes were determined and analyzed in different study parts for inter- and intra-individual variation and the impact of long- (competitive season) and short-term (all out) exercise.Median Ret% was 0.9 (CI(0.5-99.5%) 0.4-2.7). Intra-individual variation for Ret% was 0.0118; inter-individual variation 0.0124. During periods of intensive exercise Ret% was slightly lower (mean - 0.1%, p = 0.048). After a short, all-out exercise bout, Ret% was increased (+0.5%, p = 0.0028).Athletes mostly display similar Ret% than the normal population; however, intra-individual variation in athletes is higher. During the competitive season of endurance athletes, Ret% is slightly decreased. After short bouts of intense exercise Ret% is increased. These data can be used for the interpretation of blood profiles in athletes.
Authors:
Yorck Olaf Schumacher; Daniel Sahm; Manfred W Baumstark; Torben Pottgiesser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Drug testing and analysis     Volume:  2     ISSN:  1942-7611     ISO Abbreviation:  Drug Test Anal     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101483449     Medline TA:  Drug Test Anal     Country:  England    
Other Details:
Languages:  eng     Pagination:  469-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 John Wiley & Sons, Ltd.
Affiliation:
Medizinische Universitätsklinik, Universität Freiburg, Germany. olaf@msm1.ukl.uni-freiburg.de
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