| Reticulocyte count and reticulocyte maturation profile in human umbilical cord blood from healthy newborns. | |
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MedLine Citation:
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PMID: 20223743 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most fetal hematologic parameters show a significant relationship with gestational age: a linear increase is evident throughout gestation for several hematologic parameters. A few reports have described reference values for umbilical cord blood reticulocyte counts performed with automated hematology analyzers. Our aim was to use automated hematology analyzers (ADVIA 120; Siemens Healthcare Diagnostics) to establish reference intervals for reticulocyte parameters in cord blood from healthy newborns of 34 to 42 weeks of gestation. We also investigated whether differences in reticulocyte parameters exist between the sexes and between different weeks of gestation. We enrolled 98 healthy, appropriate for gestational age newborns. In term infants, the reticulocyte percentage, the absolute reticulocyte count, and the reticulocyte hemoglobin content decreased significantly as the gestational age increased, but the maturation subpopulations did not change significantly. We found no significant differences between the sexes. In conclusion, our results contribute to the establishment of reference intervals for cord blood from full-term newborns that are measured with an automated hematology analyzer. |
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Authors:
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Mariacaterina Maconi; Debora Formisano; Leandra Cavalca; Alessandro Rolfo; Simona Cardaropoli; Paolo Danise |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Laboratory hematology : official publication of the International Society for Laboratory Hematology Volume: 16 ISSN: 1523-6528 ISO Abbreviation: Lab Hematol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-12 Completed Date: 2010-07-12 Revised Date: 2010-09-28 |
Medline Journal Info:
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Nlm Unique ID: 9615688 Medline TA: Lab Hematol Country: United States |
Other Details:
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Languages: eng Pagination: 3-7 Citation Subset: IM |
Affiliation:
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Department of Laboratory Medicine, AO Arcispedale Santa Maria Nuova, Reggio Emilia, Italy. mmaconi@aslal.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Blood / cytology* Flow Cytometry Humans Infant, Newborn Infant, Premature Male Reference Values Reticulocyte Count* Reticulocytes / cytology*, physiology Term Birth |
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