| Reticulated platelet monitoring after autologous peripheral haematopoietic progenitor cell transplantation. | |
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MedLine Citation:
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PMID: 19398373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reticulated platelets are the youngest marker of megakaryopoiesis. We monitored 13 haematological patients undergoing autologous peripheral haematopoietic progenitor cell transplantation. We used a flow cytometric method based on thiazole orange platelet staining. Patients showed a fall in reticulated platelet percentage at a mean of 5 days before a nadir of the platelet count. In all cases, platelet recovery is preceded by a rise of reticulated platelets; in 10 cases patients received platelet prophylactic transfusions after RP rise. The rise in reticulated platelets is an early sign of engraftment and may represent an easy parameter for transfusion management of transplanted patients. |
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Authors:
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Giovanna Martinelli; Patrizia Merlo; Rita Fantasia; Francesco Gioia; Giovanni Crovetti |
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Publication Detail:
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Type: Journal Article Date: 2009-04-23 |
Journal Detail:
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Title: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis Volume: 40 ISSN: 1473-0502 ISO Abbreviation: Transfus. Apher. Sci. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-12 Completed Date: 2009-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101095653 Medline TA: Transfus Apher Sci Country: England |
Other Details:
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Languages: eng Pagination: 175-81 Citation Subset: T |
Affiliation:
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Servizio Immunoematologia e Medicina Trasfusionale, Azienda Ospedaliera Ospedale di Circolo di Busto Arsizio, Varese, Italy. gmartinelli@aobusto.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Female Flow Cytometry Hematopoietic Stem Cell Transplantation* Humans Male Middle Aged Peripheral Blood Stem Cell Transplantation* Platelet Count / methods* Platelet Transfusion Thrombopoiesis* Transplantation, Autologous |
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