Document Detail

Rethinking vector immunology: the role of environmental temperature in shaping resistance.
MedLine Citation:
PMID:  23147703     Owner:  NLM     Status:  MEDLINE    
Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.
Courtney C Murdock; Krijn P Paaijmans; Diana Cox-Foster; Andrew F Read; Matthew B Thomas
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-11-13
Journal Detail:
Title:  Nature reviews. Microbiology     Volume:  10     ISSN:  1740-1534     ISO Abbreviation:  Nat. Rev. Microbiol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-16     Completed Date:  2013-02-07     Revised Date:  2014-08-27    
Medline Journal Info:
Nlm Unique ID:  101190261     Medline TA:  Nat Rev Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  869-76     Citation Subset:  IM    
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MeSH Terms
Culicidae / immunology*,  parasitology*
Host-Parasite Interactions / immunology*
Insect Vectors / immunology*,  parasitology*
Grant Support
EF‑0914384//PHS HHS; R21 AI096036/AI/NIAID NIH HHS; R21 AI096036‑01/AI/NIAID NIH HHS

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