Document Detail


Resveratrol in the prevention and treatment of coronary artery disease.
MedLine Citation:
PMID:  21870059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Resveratrol is a polyphenolic compound found in red wine that is believed to be responsible for its beneficial cardiovascular effects. Extensive research in the past several decades has identified multiple mechanisms by which resveratrol modifies the cardiovascular risk factors that lead to coronary artery disease, yet translation to the clinical arena has been unexpectedly slow. In this article, we review the existing evidence regarding the beneficial effects of resveratrol and briefly discuss its potential therapeutic applications.
Authors:
Louis M Chu; Antonio D Lassaletta; Michael P Robich; Frank W Sellke
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  13     ISSN:  1534-6242     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-02     Completed Date:  2012-02-21     Revised Date:  2013-06-03    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  439-46     Citation Subset:  IM    
Affiliation:
Division of Cardiothoracic Surgery, Department of Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiovascular System / drug effects
Coronary Artery Disease / physiopathology,  prevention & control*,  therapy
Humans
Lipid Peroxidation
Lipids / blood
Macrophages / physiology
Metabolic Syndrome X / physiopathology,  therapy
Muscle, Smooth, Vascular / physiology
Myocardial Reperfusion
Plaque, Atherosclerotic / physiopathology
Stilbenes / therapeutic use*
Thrombosis / physiopathology
Wine
Chemical
Reg. No./Substance:
0/Lipids; 0/Stilbenes; Q369O8926L/resveratrol
Comments/Corrections
Erratum In:
Curr Atheroscler Rep. 2011 Dec;13(6):508

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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