Document Detail

Resuscitation great. Karel Wenckebach: the story behind the block.
MedLine Citation:
PMID:  18692289     Owner:  NLM     Status:  MEDLINE    
The first documentation of a human atrioventricular (AV) block dates back to 1873, when A.L. Galabin reported a 34-year-old patient using an apexcardiogram. This was followed the same year by Luciani, recording 2nd degree AV blocks while studying frogs. In 1899, Karel F. Wenckebach provided the cardiology field with the criteria of what he called "Luciani periods", what we now know as Wenckebach Periodicity or Mobitz I AV block. The classic electrocardiographic presentation of Mobitz I/Wenckebach periodicity is characterized by progressive prolongation of the PR interval on the electrocardiogram (EKG) on consecutive beats followed by a blocked P wave. This clinical entity is the first and most common of two types of 2nd degree AV block. This manuscript reviews the life of Karel F. Wenckebach and the events that led this great Dutch physician to make one of the most important contributions to the field of cardiology.
Natalia Mendoza-Davila; Joseph Varon
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Publication Detail:
Type:  Biography; Historical Article; Journal Article; Portraits     Date:  2008-08-08
Journal Detail:
Title:  Resuscitation     Volume:  79     ISSN:  0300-9572     ISO Abbreviation:  Resuscitation     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-27     Completed Date:  2009-02-10     Revised Date:  2009-08-25    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  189-92     Citation Subset:  IM    
Universidad de Monterrey, School of Medicine, Monterrey, Nuevo León, Mexico.
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MeSH Terms
Atrioventricular Block / history*,  physiopathology
Electrocardiography / history
History, 19th Century
Resuscitation / history*
Personal Name Subject
Personal Name Subject:
Karel F Wenchkebach

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