Document Detail

Resuscitation from traumatic shock.
MedLine Citation:
PMID:  17016404     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Shock is the body's response to decreased cellular perfusion. It can begin with hemorrhage, mechanical obstruction of the circulation, cardiac dysfunction, central nervous system injury, or sepsis. Once triggered, shock is perpetuated by the release of toxic compounds from ischemic cells. The treatment of shock consists of the removal or correction of the triggering pathology, followed by resuscitation back to the normal state. Clinical research in shock resuscitation in the past year has focused on recognizing the presence of shock in patients at risk, particularly those with normal vital signs but ongoing, occult hypoperfusion. In the laboratory, the emphasis has been on minimizing the initial hemorrhagic insult, minimizing the release of toxins from ischemic cells, and blocking the response to the toxins that are released.
R P Dutton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in anaesthesiology     Volume:  14     ISSN:  0952-7907     ISO Abbreviation:  Curr Opin Anaesthesiol     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2006-10-03     Completed Date:  2007-06-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8813436     Medline TA:  Curr Opin Anaesthesiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  217-20     Citation Subset:  -    
Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
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