Document Detail

Resurgence of congenital syphilis: diagnosis and treatment.
MedLine Citation:
PMID:  21846627     Owner:  NLM     Status:  In-Data-Review    
Despite comprehensive antenatal screening recommendations and inexpensive treatment, congenital syphilis has long been and continues to be a public health concern, causing substantial morbidity and adverse outcomes. The following article reviews syphilis etiology and presentation, clinical disease, laboratory diagnosis, and treatment of congenital syphilis. A case will be presented describing a 31-week male infant exposed to infectious syphilis in utero. The neonate presented with classic signs of infection at birth. After initial serology testing of the infant, appropriate treatment was commenced. The infant received crystalline penicillin G for a period of ten days in consultation with pediatric infectious disease specialists. As expected, the infant's rapid plasma reagin (RPR) titers declined by three and six months of age. An interdisciplinary approach provided safe and optimal care for this infant. He was discharged, stable, and thriving at 38 weeks corrected age. Long-term multidisciplinary management and follow-up were arranged.
Tara Follett; Denise F Clarke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neonatal network : NN     Volume:  30     ISSN:  1539-2880     ISO Abbreviation:  Neonatal Netw     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-08-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503921     Medline TA:  Neonatal Netw     Country:  United States    
Other Details:
Languages:  eng     Pagination:  320-8     Citation Subset:  N    
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