| The resurgence of acyclic nucleic acids. | |
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MedLine Citation:
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PMID: 20151377 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly. |
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Authors:
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Su Zhang; Christopher Switzer; John C Chaput |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
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Title: Chemistry & biodiversity Volume: 7 ISSN: 1612-1880 ISO Abbreviation: Chem. Biodivers. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-16 Completed Date: 2010-05-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101197449 Medline TA: Chem Biodivers Country: Switzerland |
Other Details:
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Languages: eng Pagination: 245-58 Citation Subset: IM |
Affiliation:
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Center for Evolutionary Functional Genomics, The Biodesign Institute, and Department of Chemistry and Biochemistry at Arizona State University, Tempe, Arizona 85287-5301, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Nanotechnology Nucleic Acid Conformation Nucleic Acids / chemical synthesis, chemistry*, drug effects Nucleosides / chemistry*, metabolism, pharmacology, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids; 0/Nucleosides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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