Document Detail


Results of a technique of pancreaticojejunostomy that optimizes blood supply to the pancreas.
MedLine Citation:
PMID:  9849731     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Anastomotic failure after pancreaticojejunostomy is still a common problem. Failure rates have not decreased perceptibly in the past 3 decades. The neck of the pancreas is a vascular watershed between celiac and superior mesenteric arterial systems. Prior attempts to reduce anastomotic failure at pancreaticojejunostomy have not focused on issues related to blood supply of the pancreas. The aim of this study was to determine whether pancreaticojejunostomy performed using a technique that included optimization of blood supply to the pancreas, would result in a low anastomotic failure rate. METHODS: The technique was prospectively evaluated in 40 patients having pancreaticojejunostomy, 39 during pancreaticoduodenectomy and 1 after traumatic transection of the neck of the pancreas. Blood supply to the pancreatic neck was evaluated clinically and by Doppler techniques. When blood supply was considered marginal, the pancreas was re-resected 1.5-2.0 cm to the left, away from the vascular watershed. RESULTS: Blood supply at the cut margin of pancreas was judged as brisk in 24 patients and marginal in 16 patients. Resecting a segment of pancreas in these 16 patients resulted in brisk bleeding from the new cut margin in all but 1 patient who had an anomalous artery that had to be sacrificed for oncologic reasons. The only fistula in the series occurred in this patient. There were no intraabdominal abscesses. CONCLUSIONS: A technique that includes ensuring adequate blood supply to the pancreas can result in a very low rate of anastomotic failure.
Authors:
S M Strasberg; M S McNevin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American College of Surgeons     Volume:  187     ISSN:  1072-7515     ISO Abbreviation:  J. Am. Coll. Surg.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1998-12-18     Completed Date:  1998-12-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9431305     Medline TA:  J Am Coll Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  591-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Washington University, St. Louis, MO, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Blood Flow Velocity / physiology
Female
Humans
Ischemia / prevention & control*
Laser-Doppler Flowmetry
Male
Middle Aged
Pancreas / blood supply*,  injuries
Pancreatic Neoplasms / surgery
Pancreaticojejunostomy / methods*
Pancreatitis / surgery
Regional Blood Flow / physiology
Surgical Wound Dehiscence / prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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