Document Detail

Results of parathyroidectomy for autonomous hyperparathyroidism.
MedLine Citation:
PMID:  475537     Owner:  NLM     Status:  MEDLINE    
Autonomous hyperparathyroidism occurred in 15% of 152 patients maintained by long-term home dialysis during the past nine years. Twenty-two patients with elevated serum parathormone levels and progressive bone disease in the presence of normal serum phosphate and calcium levels were treated by subtotal parathyroidectomy. All had parathyroid hyperplasia. Eighteen of the 22 patients are presently alive and undergo dialysis. Symptoms of bone pain, pruritus, and muscle cramps had improved in three fourths of the patients. The serum parathormone level decreased from a preoperative average of 576 muLEq/mL to an average of 188 muLEq/mL postoperatively. All 18 patients, observed for six to 77 months, showed improvement in x-ray films of their bone disease. The autonomous hyperparathyroidism of end-stage renal disease is corrected by subtotal parathyroidectomy, and the effect is sustained.
M R Swanson; J A Biggers; A R Remmers; H E Sarles; R M Nelson; J C Fish
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  139     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1979-10-24     Completed Date:  1979-10-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  989-91     Citation Subset:  AIM; IM    
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MeSH Terms
Hemodialysis, Home
Hyperparathyroidism, Secondary / etiology,  surgery*
Parathyroid Glands / surgery
Parathyroid Hormone / blood
Renal Osteodystrophy / etiology
Reg. No./Substance:
0/Parathyroid Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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