| Results of a national therapeutic trial conducted in 10,000 hypertensive patients by 2000 general practitioners. | |
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MedLine Citation:
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PMID: 282084 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. 10,294 hypertensive patients were treated and followed by 2200 general practitioners under the supervision of 130 cardiologists and nephrologists. 2. The treatment groups, randomly allocated, were designated to use three distinct antihypertensive drugs, administered alone, and combined two-by-two. 3. Some 75% of patients had a supine diastolic blood pressure of less than 95 mmHg after 4 months treatment. 4. A total of 12% of patients had dropped out by 4 months from entry; no clear relationship was established between side effects and drop out. |
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Authors:
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A Jouve; L Goldet; M Mathieu |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Clinical science and molecular medicine. Supplement Volume: 4 ISSN: 0144-4107 ISO Abbreviation: Clin Sci Mol Med Suppl Publication Date: 1978 Dec |
Date Detail:
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Created Date: 1979-03-24 Completed Date: 1979-03-24 Revised Date: 2008-02-12 |
Medline Journal Info:
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Nlm Unique ID: 7907311 Medline TA: Clin Sci Mol Med Suppl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 353s-354s Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Amiloride / therapeutic use Antihypertensive Agents* / adverse effects Drug Tolerance Female Heart Rate Humans Hydrochlorothiazide / therapeutic use Hypertension / drug therapy* Male Methyldopa / therapeutic use Middle Aged Timolol / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 2609-46-3/Amiloride; 26839-75-8/Timolol; 555-30-6/Methyldopa; 58-93-5/Hydrochlorothiazide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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