Document Detail


Results from pelvic exenteration for locally advanced colorectal cancer with lymph node metastases.
MedLine Citation:
PMID:  9556239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We examined the survival benefit of pelvic exenteration for locally advanced colorectal cancer with lymph node metastases, because this issue remains controversial. METHODS: Medical records of 50 patients who underwent curative pelvic exenteration for colorectal cancer were reviewed retrospectively. Nodal metastases were examined by the clearing method in 29 patients and by the conventional manual method in 21 patients. RESULTS: Invasion to contiguous pelvic organs was present in 40 patients (80 percent) and absent in 10 patients (20 percent). Node metastases were present in 33 patients (66 percent). Operative morbidity and mortality rates were 22 percent (11 patients) and 6 percent (3 patients), respectively. Respective five-year survival rates were 60 and 80 percent in the groups with and without organ invasion (no significant difference). Five-year survival rates in patients with nodal metastases was 54.6 percent but was significantly higher, 82.4 percent, in patients without nodal metastases. Five-year survival in 28 patients with both organ invasion and nodal metastases was 53.6 percent. CONCLUSIONS: Long-term survival was afforded by pelvic exenteration for locally advanced colorectal cancer with nodal metastases.
Authors:
J Hida; M Yasutomi; T Maruyama; A Nakajima; T Uchida; T Wakano; T Tokoro; K Fujimoto
Related Documents :
9826479 - Primary surgical cure of stage iii-b cervical carcinoma with adnexal metastasis.
18425339 - Prophylactic pelvic irradiation as part of primary therapy in uterine sarcomas.
11426959 - Neuroendocrine cervical carcinoma: a diagnostic and therapeutic challenge.
2464779 - Endodermal sinus tumor of the infant vagina treated exclusively by chemotherapy.
9870789 - Prognostic factors in patients with with locally advanced cervical cancer treated with ...
11748979 - The clinical course of deep vein thrombosis in patients with gynecologic cancer.
18831719 - First- and second-line treatment of advanced metastatic non-small-cell lung cancer: a g...
16062079 - Organ preservation and treatment toxicity with induction chemotherapy followed by radia...
8698739 - Modulation of multidrug resistance by dexverapamil in epoch-refractory lymphomas.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diseases of the colon and rectum     Volume:  41     ISSN:  0012-3706     ISO Abbreviation:  Dis. Colon Rectum     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-05-06     Completed Date:  1998-05-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372764     Medline TA:  Dis Colon Rectum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  165-8     Citation Subset:  IM    
Affiliation:
The First Department of Surgery, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Colorectal Neoplasms / mortality,  surgery*
Female
Humans
Lymphatic Metastasis*
Male
Pelvic Exenteration*
Prognosis
Retrospective Studies
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Surgical treatment of piles: prospective, randomized study of Parks vs. Milligan-Morgan hemorrhoidec...
Next Document:  New method of radiotherapy for anal cancer with three-dimensional tumor reconstruction based on endo...