| Results of directly observed treatment for tuberculosis in Ensenada, Mexico: not all DOTS programs are created equally. | |
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MedLine Citation:
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PMID: 17352094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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SETTING: Tuberculosis (TB) program in Ensenada, Mexico. OBJECTIVE: To evaluate the impact of the DOTS strategy on adherence and cure rates in everyday practice. DESIGN: Retrospective analysis of 629 patients diagnosed with TB. MEASUREMENTS AND RESULTS: A total of 70% of the patients under directly observed treatment (DOT) were cured vs. 72.8% of those under self-administered treatment (SAT, P = 0.57). There was no difference on the length of therapy according to treatment regimen (4.82 +/- 2.41 for DOT vs. 4.93 +/- 2.16 for SAT, P = 0.61); 16.8% of patients under DOT abandoned treatment vs. 14.1% in the SAT group (P = 0.40). Logistic regression analysis confirmed the previous findings, with length of treatment under 6 months being the strongest predictive variable for treatment failure (OR 18.8, P < 0.00). The type of regimen (DOT vs. SAT) was not predictive of treatment failure (OR for failure for SAT regimen 0.65, P = 0.14). CONCLUSIONS: Cure and completion of treatment rates in our population under study did not differ significantly when comparing DOT vs. SAT. Those in charge of the DOTS programs in a given country need to assess which are the most important ingredients for success in their particular program. |
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Authors:
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P Radilla-Chávez; R Laniado-Laborín |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Volume: 11 ISSN: 1027-3719 ISO Abbreviation: Int. J. Tuberc. Lung Dis. Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-03-13 Completed Date: 2007-04-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706389 Medline TA: Int J Tuberc Lung Dis Country: France |
Other Details:
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Languages: eng Pagination: 289-92 Citation Subset: IM |
Affiliation:
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Graduate School of Public Health, Universidad Autónoma de Baja California, Tijuana, México. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Antitubercular Agents / therapeutic use* Child Child, Preschool Communicable Disease Control / standards* Directly Observed Therapy / standards* Female Humans Infant Logistic Models Male Mexico / epidemiology Middle Aged Patient Compliance Retrospective Studies Treatment Outcome Tuberculosis, Multidrug-Resistant Tuberculosis, Pulmonary / drug therapy*, epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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