| Results of directional peripheral atherectomy with reference to histology, histochemistry, and ultrastructure. | |
| | |
MedLine Citation:
|
PMID: 8503511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
One hundred patients with symptomatic peripheral vascular disease were treated with a directional atherectomy catheter; 153 lesions comprising 98 stenoses and 55 occlusions were located in the iliac (n = 22), superficial femoral (n = 114), popliteal (n = 16), and anterior tibial (n = 1) arteries. The majority of these patients were poor candidates for balloon angioplasty because of the complexity of lesions. There were 70 eccentric and 28 concentric lesions and 55 occlusions (mean length 4.2 +/- 2.9 cm). Acute success rate was 94% for both stenoses and occlusions. Four patients were treated in both lower extremities. The stenoses were reduced from 85 +/- 12% to 12 +/- 10% acutely (occlusions 100% to 9 +/- 9%). Six-month angiographic follow-ups were performed in 81% of treated patients, the others refusing angiography. Mean stenosis after six months was 33 +/- 25% (occlusions 44 +/- 28%). Restenosis (> 50%) was found in 20% of treated lesions: 26% in concentric lesions, 8% in eccentric lesions, and 32% in occluded vessels. Treatment of peripheral vascular disease with the atherectomy device is safe and effective therapy with good long-term results. These results were obtained in complex lesions with 55 occlusions. Atherectomy seems to be particularly beneficial in the treatment of eccentric and complex stenoses and is not limited by occlusion or calcification. Furthermore, insight into the pathogenesis of arteriosclerosis and the development of restenosis is enabled by analysis of removed plaque material. |
| | |
Authors:
|
P Gonschior; B Höfling; B Mack; L Simpson; F Gerheuser; A Nerlich; G Bauriedel; U Welsch |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Angiology Volume: 44 ISSN: 0003-3197 ISO Abbreviation: Angiology Publication Date: 1993 Jun |
Date Detail:
|
Created Date: 1993-06-29 Completed Date: 1993-06-29 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0203706 Medline TA: Angiology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 454-63 Citation Subset: IM |
Affiliation:
|
Med. Dept. I, Klinikum Grosshadern, München, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Atherectomy / instrumentation, methods*, statistics & numerical data Female Femoral Artery / metabolism, pathology, surgery Follow-Up Studies Histocytochemistry Humans Iliac Artery / metabolism, pathology, surgery Male Middle Aged Peripheral Vascular Diseases / epidemiology, metabolism, pathology, surgery* Popliteal Artery / metabolism, pathology, surgery Reoperation / statistics & numerical data Tibial Arteries / metabolism, pathology, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prevalence of ventricular premature complexes in healthy and untreated hypertensive elderly people.
Next Document: The importance of the subfascial lymphatics in the diagnosis of lower limb edema: investigations wit...