Document Detail


Results of a multi-institutional benchmark test for cranial CT/MR image registration.
MedLine Citation:
PMID:  20381270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Variability in computed tomography/magnetic resonance imaging (CT/MR) cranial image registration was assessed using a benchmark case developed by the Quality Assurance Review Center to credential institutions for participation in Children's Oncology Group Protocol ACNS0221 for treatment of pediatric low-grade glioma.
METHODS AND MATERIALS: Two DICOM image sets, an MR and a CT of the same patient, were provided to each institution. A small target in the posterior occipital lobe was readily visible on two slices of the MR scan and not visible on the CT scan. Each institution registered the two scans using whatever software system and method it ordinarily uses for such a case. The target volume was then contoured on the two MR slices, and the coordinates of the center of the corresponding target in the CT coordinate system were reported. The average of all submissions was used to determine the true center of the target.
RESULTS: Results are reported from 51 submissions representing 45 institutions and 11 software systems. The average error in the position of the center of the target was 1.8 mm (1 standard deviation = 2.2 mm). The least variation in position was in the lateral direction. Manual registration gave significantly better results than did automatic registration (p = 0.02).
CONCLUSION: When MR and CT scans of the head are registered with currently available software, there is inherent uncertainty of approximately 2 mm (1 standard deviation), which should be considered when defining planning target volumes and PRVs for organs at risk on registered image sets.
Authors:
Kenneth Ulin; Marcia M Urie; Joel M Cherlow
Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, N.I.H., Extramural     Date:  2010-04-08
Journal Detail:
Title:  International journal of radiation oncology, biology, physics     Volume:  77     ISSN:  1879-355X     ISO Abbreviation:  Int. J. Radiat. Oncol. Biol. Phys.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-08-12     Revised Date:  2011-08-03    
Medline Journal Info:
Nlm Unique ID:  7603616     Medline TA:  Int J Radiat Oncol Biol Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1584-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Quality Assurance Review Center, Providence, RI, USA.
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MeSH Terms
Descriptor/Qualifier:
Benchmarking / standards*
Brain Neoplasms / diagnosis*,  radiography
Child
Glioma / diagnosis*,  radiography
Humans
Magnetic Resonance Imaging / methods*,  standards
Radiotherapy Planning, Computer-Assisted / methods,  standards
Software
Tomography, X-Ray Computed / methods*,  standards
Grant Support
ID/Acronym/Agency:
5U10CA029511/CA/NCI NIH HHS; U10 CA029511-30/CA/NCI NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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