| Results of the 2nd part Scientific Workshop of the ECCO (II): Measures and markers of prediction to achieve, detect, and monitor intestinal healing in Inflammatory Bowel Disease. | |
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MedLine Citation:
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PMID: 21939926 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The healing of the intestine is becoming an important objective in the management of inflammatory bowel diseases. It is associated with improved disease outcome. Therefore the assessment of this healing both in clinical studies and routine practice is a key issue. Endoscopy for the colon and terminal ileum and computerized tomography or magnetic resonance imaging for the small bowel are the most direct ways to evaluate intestinal healing. However, there are many unsolved questions about the definition and the precise assessment of intestinal healing using these endoscopic and imaging techniques. Furthermore, these are relatively invasive and expensive procedures that may be inadequate for regular patients' monitoring. Therefore, biomarkers such as C-reactive protein and fecal calprotectin have been proposed as surrogate markers for intestinal healing. Nevertheless, the sensitivity and specificity of these markers for the prediction of healing may be insufficient for routine practice. New stool, blood or intestinal biomarkers are currently studied and may improve our ability to monitor intestinal healing in the future. |
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Authors:
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Marco Daperno; Fabiana Castiglione; Lissy de Ridder; Iris Dotan; Martti Färkkilä; Jon Florholmen; Gerald Fraser; Walter Fries; Xavier Hebuterne; Peter Laszlo Lakatos; Julián Panés; Jordi Rimola; Edouard Louis |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-11 |
Journal Detail:
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Title: Journal of Crohn's & colitis Volume: 5 ISSN: 1876-4479 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-9-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101318676 Medline TA: J Crohns Colitis Country: - |
Other Details:
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Languages: ENG Pagination: 484-498 Citation Subset: - |
Copyright Information:
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Copyright © 2011 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Gastroenterology Division, AO Ordine Mauriziano, Torino, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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