| Restriction of placental vasculature in a non-human primate: A unique model to study placental plasticity. | |
| | |
MedLine Citation:
|
PMID: 22030304 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The limits of placental plasticity, i.e., the ability of the placenta to adapt and alter its growth trajectory in response to altered fetal requirements, are not known. We report fetal and placental hemodynamic adaptations in a novel non-human primate model in which the fetal inter-placental bridging vessels were surgically ligated. Doppler ultrasound studies showed that the rhesus placenta compensates for an approximate 40% reduction in functional capacity by increased growth and maintenance of umbilical volume blood flow. This unique experimental animal model has applications for mechanistic studies of placental plasticity and the impact on fetal development. |
| | |
Authors:
|
V H J Roberts; J P Räsänen; M J Novy; A Frias; S Louey; T K Morgan; K L Thornburg; E R Spindel; P L Grigsby |
Related Documents
:
|
22092404 - Unexplained fetal death has a biological signature of maternal anti-fetal rejection: ch... 11778994 - First-trimester sonographic umbilical cord diameter and the growth of the human embryo. 15305344 - The impact of fetal renal pelvic diameter on postnatal outcome. 16532914 - Is fetal growth impaired after in vitro fertilization? 7026014 - Maternal nutrition in pregnancy. part ii: the implications of previous gastrointestinal... 11943744 - Predictive value of hormone measurements in maternal and fetal complications of pregnancy. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-24 |
Journal Detail:
|
Title: Placenta Volume: - ISSN: 1532-3102 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8006349 Medline TA: Placenta Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center (ONPRC), Oregon Health & Science University, 505 NW 185th Ave, Beaverton, OR 97006, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Point Defect Clusters and Dislocations in FIB Irradiated Nanocrystalline Aluminum Films: An Electron...
Next Document: Prevalence of Risk Factors for Contrast-Induced Nephrotoxicity in Outpatients Undergoing Intravenous...