| Restoring the metabolic disturbance of zinc: may not only contribute to the prevention of esophageal squamous cell cancer. | |
| | |
MedLine Citation:
|
PMID: 18707814 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The relationship between zinc deficiency (ZD) and esophageal squamous cell cancer (ESCC) is well-established. Zinc supplement has long been considered as potential strategy for prevention of ESCC. However, the effect of zinc replenishment on prevention of ESCC is still in controversy and no convincing evidence to support these proposals has become known. We hypothesized that zinc deficiency might be the major initiator for dysfunction of numerous genes and subsequent carcinogenesis of esophagus, and replenishment of zinc might improve the prognosis of patients with ESCC. |
| | |
Authors:
|
Wei Guo; Yun-Ping Zhao; Yao-Guang Jiang; Ru-Wen Wang; Zheng Ma |
Related Documents
:
|
16428034 - Epidemiology and molecular biology of barrett esophagus. 11082084 - Final results from 10 year cohort of patients undergoing surveillance for barrett's oes... 14748664 - Multimodality therapy for cancers of the esophagus and gastric cardia. 11018394 - The excess incidence of squamous cell esophageal cancer among us black men. role of soc... 17088244 - Health-related quality of life for latino survivors of childhood cancer. 16231334 - Cancer incidence of persons with down syndrome in finland: a population-based study. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-08-15 |
Journal Detail:
|
Title: Medical hypotheses Volume: 71 ISSN: 0306-9877 ISO Abbreviation: Med. Hypotheses Publication Date: 2008 Dec |
Date Detail:
|
Created Date: 2009-01-01 Completed Date: 2009-02-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: Scotland |
Other Details:
|
Languages: eng Pagination: 957-9 Citation Subset: IM |
Affiliation:
|
Department of Thoracic Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Carcinoma, Squamous Cell
/
epidemiology*,
prevention & control Deficiency Diseases / complications*, prevention & control Esophageal Neoplasms / epidemiology*, prevention & control Homeostasis Humans Zinc / blood, deficiency*, therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Exercise interval training: an improved stimulus for improving the physiology of pre-diabetes.
Next Document: A novel strategy for prefabrication of large and axially vascularized tissue engineered bone by usin...