| Restored cardiac conditions and left ventricular function after parathyroidectomy in a hemodialysis patient. Parathyroidectomy improves cardiac fatty acid metabolism assessed by 123I-BMIPP. | |
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MedLine Citation:
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PMID: 19179778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 62 year-old female hemodialysis patient underwent parathyroidectomy to treat secondary hyperparathyroidism. On the preoperative assessment, the plasma levels of parathyroid hormone (PTH) and B-type natriuretic peptide (BNP) were elevated. Echocardiography showed reduced left ventricular (LV) contraction. Myocardial iodine-123-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid ((123)I-BMIPP) scintigraphy showed moderately reduced tracer uptake in the postero-inferior area on single-photon emission computed tomography and decreased washout on the planar images. After parathyroidectomy, the plasma levels of PTH and BNP decreased, followed by improvement in LV contraction. Myocardial (123)I-BMIPP scintigraphy revealed that the washout on planar images had increased, which suggests that myocardial (123)I-BMIPP scintigraphy is useful for estimating the effect of parathyroidectomy on cardiac function. |
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Authors:
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Mamoru Nanasato; Norihiko Goto; Satoshi Isobe; Kazumasa Unno; Haruo Hirayama; Tetsuhiko Sato; Susumu Matsuoka; Takaharu Nagasaka; Yoshihiro Tominaga; Kazuharu Uchida; Toyoaki Murohara |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-01-27 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 73 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-25 Completed Date: 2009-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 1956-60 Citation Subset: IM |
Affiliation:
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Cardiovascular Center, Nagoya Daini Red Cross Hospital, Japan. nana@nagoya2.jrc.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Echocardiography Fatty Acids / diagnostic use, metabolism* Female Humans Hyperparathyroidism, Secondary / etiology, metabolism, surgery* Iodine Radioisotopes Iodobenzenes / diagnostic use* Kidney Failure, Chronic / complications, metabolism, therapy Middle Aged Myocardial Contraction Myocardium / metabolism* Natriuretic Peptide, Brain / blood Parathyroid Hormone / blood Parathyroidectomy* Radiopharmaceuticals / diagnostic use* Recovery of Function Renal Dialysis* Stroke Volume Tomography, Emission-Computed, Single-Photon Treatment Outcome Ventricular Dysfunction, Left / etiology, metabolism, physiopathology, radionuclide imaging* Ventricular Function, Left* |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Fatty Acids; 0/Iodine Radioisotopes; 0/Iodobenzenes; 0/Parathyroid Hormone; 0/Radiopharmaceuticals; 114471-18-0/Natriuretic Peptide, Brain; 116754-87-1/iodofiltic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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