| Restless legs syndrome presenting as an acute exacerbation of multiple sclerosis. | |
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MedLine Citation:
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PMID: 22096645 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Restless legs syndrome is common in patients with multiple sclerosis but has not been reported as occurring due to an acute, inflammatory, demyelinating attack. Restless legs syndrome is known to be related to low brain iron levels. Multiple sclerosis has been associated with the abnormal accumulation of iron in the chronic, progressive phase of axonal degeneration. Iron deficiency may play a role in demyelination. This suggests that restless legs syndrome may be caused by the inflammatory, demyelinating component of multiple sclerosis rather than axonal degeneration. The author presents a case of self-limited restless legs syndrome occurring as an acute attack of multiple sclerosis, supporting the notion that inflammatory demyelination is the underlying pathophysiology of restless legs syndrome in multiple sclerosis. |
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Authors:
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James H Bernheimer |
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Publication Detail:
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Type: Journal Article Date: 2011-07-05 |
Journal Detail:
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Title: Multiple sclerosis international Volume: 2011 ISSN: 2090-2662 ISO Abbreviation: Mult Scler Int Publication Date: 2011 |
Date Detail:
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Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101566861 Medline TA: Mult Scler Int Country: Egypt |
Other Details:
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Languages: eng Pagination: 872948 Citation Subset: - |
Affiliation:
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Mercy Medical Center, Baltimore, MD 21202, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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