| Restless legs syndrome in patients with amyotrophic lateral sclerosis. | |
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MedLine Citation:
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PMID: 20669314 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We aimed to evaluate the frequency and determinants of restless legs syndrome (RLS) in a group of 76 patients with amyotrophic lateral sclerosis (ALS) and 100 control subjects. A diagnosis of RLS was made according to the criteria of the International RLS Study Group, and severity was assessed by the RLS severity scale. RLS was significantly more frequent in patients with ALS (ALS/RLS(+)) than in control subjects (25% vs. 8%; P = 0.002). Compared with control subjects, patients with ALS/RLS(+) showed shorter history of RLS complaints and higher frequency of symptoms occurrence. Moreover, compared with those without RLS, patients with ALS/RLS(+) showed increased functional impairment and more often reported sleep complaints. Multivariate logistic regression confirmed the association between RLS and functional impairment. Our findings suggest that RLS should be considered as a possible cause of disrupted sleep in patients with ALS and should be specifically investigated in these patients. |
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Authors:
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Daniele Lo Coco; Federico Piccoli; Vincenzo La Bella |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 25 ISSN: 1531-8257 ISO Abbreviation: Mov. Disord. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 2658-61 Citation Subset: IM |
Copyright Information:
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© 2010 Movement Disorder Society. |
Affiliation:
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Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Università di Palermo, Palermo, Italy. danielelococo@yahoo.com |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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