Document Detail

Resting metabolism in hypoxia-acclimated rats during acute hypoxic exposure.
MedLine Citation:
PMID:  6290724     Owner:  NLM     Status:  MEDLINE    
In contrast to the decreased metabolism in non-hypoxia-acclimated (CT) rats, acute hypoxia (9.5% O2) did not change the resting metabolism in hypoxia-acclimated (HX: 12% O2 for 2 months) rats at 25 degrees C. After beta-adrenergic blockade, acute hypoxia greatly reduced the resting metabolism in HX rats. The calorigenic response to norepinephrine (0.4 mg . kg-1) during acute hypoxia was, however, identical with that observed in CT rats. These results suggest an enhanced beta-adrenergic stimulation in HX rats during acute-exposure to hypoxia.
M Hayashi; T Nagasaka
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Japanese journal of physiology     Volume:  32     ISSN:  0021-521X     ISO Abbreviation:  Jpn. J. Physiol.     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2007-03-21    
Medline Journal Info:
Nlm Unique ID:  2985184R     Medline TA:  Jpn J Physiol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  487-91     Citation Subset:  IM; S    
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MeSH Terms
Anoxia / metabolism*
Norepinephrine / pharmacology
Oxygen Consumption*
Rats, Inbred Strains
Receptors, Adrenergic, beta / physiology
Reg. No./Substance:
0/Receptors, Adrenergic, beta; 51-41-2/Norepinephrine

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