Document Detail

Resting measures and physiological responses to exercise for the determination of prognosis in patients with chronic heart failure: useful tools for clinical decision-making.
MedLine Citation:
PMID:  20539100     Owner:  NLM     Status:  MEDLINE    
Despite recent advances in the management of chronic heart failure (CHF), the prognosis of many of these patients remains dire. The need for an accurate prognosis in these patients has led to the identification of several indicators purported to represent the impact of the disease. Such indicators often are obtained at rest and are not always accurate at determining the clinical status of CHF patients. As a result, the relationship between prognostic indicators and clinical outcomes is frequently weak. On the other hand, physiological responses to acute exercise may unmask patients with the worst clinical status and identify those at increased risk of poor outcomes. Therefore, the present review appraises the value of several prognostic indicators for patients with CHF collected at rest and in response to exercise. In particular, it contrasts the value and accuracy of predictors of mortality widely used in clinical settings, such as oxygen uptake, ventilatory efficiency, and left ventricular ejection fraction, with new and more direct indicators of ventricular systolic and diastolic function.
Alberto Jorge Alves; Fernando Ribeiro; Moran Sagiv; Nir Eynon; Chen Yamin; Michael Sagiv; José Oliveira
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cardiology in review     Volume:  18     ISSN:  1538-4683     ISO Abbreviation:  Cardiol Rev     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-06-11     Completed Date:  2010-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-7     Citation Subset:  IM    
The Research Centre in Physical Activity, Health and Leisure, University of Porto, Faculty of Sport, Porto, Portugal.
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MeSH Terms
Chronic Disease
Echocardiography, Doppler
Exercise Tolerance*
Heart Failure / diagnosis*,  physiopathology*
Heart Function Tests / methods
Oxygen Consumption
Predictive Value of Tests
Pulmonary Gas Exchange

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