Document Detail

Resting and exercising cardiorespiratory variables and acute mountain sickness.
MedLine Citation:
PMID:  20608004     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The incidence of Acute Mountain Sickness (AMS) is increasing. In a military context our current operational areas include mountainous regions with the implications of AMS including loss of operational tempo and logistical overstretch. Oxygen saturation and heart rate variability have in some studies been predictive of AMS while in others not. No single factor has been demonstrated consistently to be predictive of developing AMS. METHODS: During an expedition to climb Mt Aconcagua (6959m) we explored the relationship between cardiorespiratory variables and AMS. In 11 subjects we measured simple physiological variables and Lake Louise Score both pre and post a standardised exercise challenge at on arrival at different altitudes and after a period of acclimatization. RESULTS: The changes in cardiorespiratory variables we observed with altitude were consistent with previous studies. Heart rate, respiratory rate and blood pressure increased whilst oxygen saturation reduced. Over time at altitude, respiratory rate and heart rate were maintained whilst there was a reduction in blood pressure towards sea level values. Oxygen saturations improved over time at altitude and the change in heart rate on exercise was reduced with acclimatization. In this small pilot study individuals with AMS may have a greater heart rate response to exercise than non-AMS subjects and this may warrant further investigation. CONCLUSIONS: The incidence of AMS in our study was low reflecting a conservative ascent profile. Further larger studies are necessary to fully assess the predictive value of cardiorespiratory variables in AMS.
T J Hooper; D Z H Levett; A J Mellor; M P W Grocott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal Naval Medical Service     Volume:  96     ISSN:  0035-9033     ISO Abbreviation:  J R Nav Med Serv     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-07     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503111     Medline TA:  J R Nav Med Serv     Country:  England    
Other Details:
Languages:  eng     Pagination:  6-12     Citation Subset:  IM    
Anaesthetic Department, Bristol Royal Infirmary.
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MeSH Terms
Acute Disease
Altitude Sickness / epidemiology,  physiopathology*
Blood Pressure / physiology
Cardiovascular Physiological Phenomena*
Great Britain
Heart Rate / physiology
Middle Aged
Military Personnel*
Oxygen Consumption / physiology
Pilot Projects
Respiratory Rate / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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