| Resting echocardiographic assessments of left atrial function and filling pressure interest in the understanding of exercise capacity in patients with chronic congestive heart failure. | |
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MedLine Citation:
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PMID: 18187295 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Doppler echocardiography is well recognized as the primary noninvasive imaging technique to assess global and regional cardiac function. Cardiopulmonary exercise testing has become a powerful tool to predict outcome in chronic heart failure (CHF). We looked for cardiac determinants, using resting echocardiographic parameters, of exercise tolerance in patients with CHF. METHODS: Transthoracic echocardiography and standardized cardiopulmonary exercise testing were performed in 75 patients (59 +/- 11 years) with CHF, New York Heart Association functional class II to III. Systolic and diastolic function, filling pressures, and left ventricular, right ventricular, and left atrial (LA) regional function were assessed using Doppler tissue velocities and strain values. RESULTS: Maximal workload (86 +/- 41 W) and peak oxygen (14.6 +/- 3.1 mL/min/kg) correlated with left ventricular filling pressure estimates (E/Ea and E/Vp) but also with end-diastolic pulsed Doppler tissue velocity at the mitral annulus (Aa), LA volume, and regional LA function assessed by strain analysis. In multivariate analysis, maximum workload and peak oxygen were shown to correlate with right ventricular peak strain, although Aa and E/Ea were the best predictors of exercise capacity. CONCLUSION: Capacity to exercise in patients with CHF is understandable by resting echocardiography. Filling pressures, and LA and right ventricular functions, are its cardiac best determinants. Adding Aa peak velocity in resting echocardiographic evaluation of patients with CHF is found useful. |
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Authors:
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Erwan Donal; Pascale Raud-Raynier; Christian De Place; Renaud Gervais; Arnaud Rosier; Manuel Roulaud; Anne Ingels; François Carre; Jean-Claude Daubert; André Denjean |
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Publication Detail:
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Type: Journal Article Date: 2008-01-09 |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 21 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-02 Completed Date: 2008-09-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 703-10 Citation Subset: IM |
Affiliation:
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Department of Cardiology, University Hospital Rennes, Rennes, France. erwan.donal@chu-rennes.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Function, Left* Chronic Disease Echocardiography, Doppler* Exercise Test Exercise Tolerance* Female Heart Atria / ultrasonography* Heart Failure / ultrasonography* Humans Male Middle Aged Oxygen Consumption Prognosis Prospective Studies Rest* Systole Treatment Outcome Ventricular Dysfunction, Left / ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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