Document Detail

Resting autonomic modulations and the heart rate response to exercise.
MedLine Citation:
PMID:  20496043     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Identify the underlying role of resting heart rate variability (HRV) in the hearts response to graded exercise testing (GXT).
METHODS: Resting 5-min HRV and heart rate (HR) measurements were made in 33 volunteers (19 males, median age 34, range 25-63 years and 14 females median age 48, range 21-63 years). Measures of VO2 peak and HR obtained during a maximal GXT and heart rate recovery (HRR) post-GXT were assessed for associations with resting HRV. Differences and effect size (d) for measures of HRV were assessed between groups based on established risk cut-points for resting, exercise and recovery HR responses.
RESULTS: Small associations were observed for the majority of resting HRV and GXT HR responses (best r value = -0.27, P > 0.05). Measures of HRV demonstrated moderate associations with HRR (best r value = 0.46, P < 0.05) and were able to predict a negative risk HRR. In contrast to other dependent variables, measures of HRV were consistently able to demonstrate significant and moderate to large (d = 0.9-2.0) differences between groups based on literature defined prognostic HR cut-points.
INTERPRETATION: Small associations with HR responses to exercise prevent their accurate prediction from resting HRV. Data support the use of vagally mediated resting HRV in predicting better HRR. Lower resting autonomic modulations underlined high risk resting and exercise HR responses. Resting short-term HRV measurements should be considered when assessing cardiac autonomic health from the HR response before, during and/or after exercise.
David Nunan; Djordje G Jakovljevic; Gay Donovan; Lynette D Singleton; Gavin R H Sandercock; David A Brodie
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Publication Detail:
Type:  Journal Article     Date:  2010-05-22
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  20     ISSN:  1619-1560     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-06-28     Completed Date:  2010-09-30     Revised Date:  2014-02-19    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  213-21     Citation Subset:  IM    
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MeSH Terms
Autonomic Nervous System / physiology*
Exercise / physiology*
Exercise Test
Heart Rate / physiology*
Middle Aged
Grant Support
MC_G0802536//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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