Document Detail


Rest and exercise hemodynamic studies in patients with isolated aortic stenosis.
MedLine Citation:
PMID:  758984     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemodynamic data obtained during rest and exercise in 22 patients with aortic stenosis were analyzed. Mean aortic valve gradient for the group did not change significantly during exercise but there was large individual variability. Aortic valve flow increased during exercise in all but 2 patients. There was no correlation between change in gradient and change in flow during exercise. Although the mean calculated aortic valve area for the group did not change significantly during exercise, the calculated area was larger during exercise in most patients. Change in the calculated valve area correlated best with changes in aortic valve flow, left ventricular stroke work index, and the product of left ventricular systolic pressure and stroke volume. This suggests that in some patients there may be a dynamic component to aortic valve obstruction that may vary with changing hemodynamics.
Authors:
J W Richardson; F L Anderson; T J Tsagaris
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cardiology     Volume:  64     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1979  
Date Detail:
Created Date:  1979-03-28     Completed Date:  1979-03-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1-11     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aortic Valve Stenosis / physiopathology*
Cardiac Output
Coronary Circulation
Heart Rate
Hemodynamics*
Humans
Middle Aged
Oxygen Consumption
Physical Exertion*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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