Document Detail

Responsiveness to change [corrected] due to supportive-expressive group therapy, improvement in mood and disease progression in women with metastatic breast cancer.
MedLine Citation:
PMID:  17503220     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the responsiveness of six questionnaires using three hypotheses of change: (i) change due to supportive-expressive group therapy (SEGT), (ii) improved mood defined as a small effect size (.2) on Profile of Mood States (POMS) Total Mood Disturbance score and (iii) progression of disease. METHOD: Data from the "Breast Expressive-Supportive Therapy" study, a multicentre randomized controlled trial of change due to SEGT versus standard of care in women with metastatic breast cancer were used. Questionnaires studied were: POMS, Impact of Event Scale, Psychosocial Adjustment to Illness Scale (PAIS), EORTC QLQ-C30, Mental Adjustment to Cancer and a Pain visual analog scale (VAS). Responsiveness to change was evaluated using the standardized response mean. POMS was used as the standard. RESULTS: POMS was the most responsive questionnaire to change due to SEGT. Questionnaires measuring psychosocial attributes were responsive to improvement in mood. EORTC QLQ-C30, PAIS, PAIN VAS and MAC were the most responsive to disease progression. More responsive questionnaires were associated with the smallest sample size required to detect an effect. CONCLUSIONS: Responsiveness to change is context specific. The POMS was the most responsive questionnaire to psychosocial therapy.
Julie Lemieux; Dorcas E Beaton; Sheilah Hogg-Johnson; Louise J Bordeleau; Jon Hunter; Pamela J Goodwin
Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2007-05-15
Journal Detail:
Title:  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation     Volume:  16     ISSN:  0962-9343     ISO Abbreviation:  Qual Life Res     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-27     Completed Date:  2007-10-25     Revised Date:  2007-11-13    
Medline Journal Info:
Nlm Unique ID:  9210257     Medline TA:  Qual Life Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1007-17     Citation Subset:  IM    
Département d'hématologie, Unité de recherche en santé des populations, Centre hospitalier affilié universitaire de Québec, pavillon St-Sacrement, Quebec, Canada.
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MeSH Terms
Adaptation, Psychological*
Breast Neoplasms / pathology,  psychology*,  therapy
Disease Progression
Middle Aged
Mood Disorders / prevention & control,  psychology,  therapy*
Psychometrics / instrumentation*
Psychotherapy, Group / methods*
Quality-Adjusted Life Years
Questionnaires / standards
Sickness Impact Profile*
Social Support*
Treatment Outcome
Erratum In:
Qual Life Res. 2007 Oct;16(8):1451

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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