Document Detail

Responsiveness and minimal clinically important differences after cholecystectomy: GIQLI versus SF-36.
MedLine Citation:
PMID:  18454301     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: To compare responsiveness and minimal clinically important differences (MCID) between the Gastrointestinal Quality of Life (GIQLI) and the Short Form 36 (SF-36), we prospectively analyze 159 patients undergoing cholecystectomy at two tertiary academic hospitals. PATIENTS AND METHODS: All patients completed the disease-specific GIQLI and the generic SF-36 before and 3 months after surgery. Scores using these instruments were interpreted by generalized estimating equation before and after cholecystectomy. The bootstrap estimation was used to derive 95% confidence intervals for differences in the responsiveness estimates. RESULTS AND DISCUSSION: Mean changes in all GIQLI and the SF-36 subscales were statistically significant (p < 0.05). Comparisons of effect size (ES), standardized response means (SRM), and relative efficiency (>1) indicated that the responsiveness of the GIQLI was superior to that of the SF-36. In the equivalence test, all lower or upper confidence limits presented no equivalence (>5), indicating good MCID. The ES and SRM for emotions and physical function in the GIQLI significantly differed from those of the SF-36 (p < 0.05). CONCLUSION: The data in this study indicate that clinicians and health researchers should weight disease-specific measures more heavily than generic measures when evaluating treatment outcomes.
Hon-Yi Shi; Hao-Hsien Lee; Chong-Chi Chiu; Herng-Chia Chiu; Yih-Huei Uen; King-Teh Lee
Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2008-05-03
Journal Detail:
Title:  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract     Volume:  12     ISSN:  1873-4626     ISO Abbreviation:  J. Gastrointest. Surg.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-27     Completed Date:  2008-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706084     Medline TA:  J Gastrointest Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1275-82     Citation Subset:  IM    
Graduate Institute of Healthcare Administration, Kaohsiung Medical University, 100-Shih-Chun 1st Road, Kaohsiung, Taiwan.
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MeSH Terms
Aged, 80 and over
Cholecystectomy / methods*
Follow-Up Studies
Health Status Indicators*
Middle Aged
Patient Satisfaction
Postoperative Period
Quality of Life*
Treatment Outcome

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