Document Detail

Responses to isoproterenol in a general population sample.
MedLine Citation:
PMID:  736356     Owner:  NLM     Status:  MEDLINE    
The response of forced expiratory flow to inhalation of isoproterenol was evaluated in a general population sample of 1,063 subjects. Percentage changes in the forced expiratory volume in 1 sec and in the maximal flow measured at 50 percent of the initial expired forced vital capacity appeared to be the best indicators of responsiveness to bronchodilator. Subjects with a history of asthma more often showed responsiveness than did the remainder of the population, even when their initial function was within normal limits. Over-all, a high proportion of subjects with abnormalities in baseline forced expiratory volume in 1 sec or maximal flow after exhalation of 50 per cent of the forced vital capacity showed sufficient improvement after bronchodilator to cause their values after isoproterenol to fall within the normal range. The data suggest that responsiveness to bronchodilator aerosol may be a useful guide to the presence of bronchial reactivity in epidemiologic studies of obstructive airway diseases.
D B Lorber; W Kaltenborn; B Burrows
Related Documents :
22107086 - Expression of extracellular matrix components and related growth factors in human tendo...
21307366 - Effect of n-2-mercaptopropionyl glycine (mpg) on exercise-induced cardiac adaptations.
6474386 - Effect of positive ionisation of inspired air on the response of asthmatic children to ...
4010796 - Effect of ni2+ on the multiphasic positive inotropic responses to histamine mediated by...
7802236 - Administration of rocuronium (org 9426) by continuous infusion and its reversibility wi...
16923446 - Effect of enhanced external counterpulsation on resting oxygen uptake in patients havin...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American review of respiratory disease     Volume:  118     ISSN:  0003-0805     ISO Abbreviation:  Am. Rev. Respir. Dis.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-03-28     Completed Date:  1979-03-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370523     Medline TA:  Am Rev Respir Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  855-61     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Asthma / diagnosis,  physiopathology
Forced Expiratory Volume
Isoproterenol / diagnostic use,  pharmacology*
Lung Diseases, Obstructive / diagnosis,  physiopathology
Maximal Expiratory Flow Rate
Maximal Expiratory Flow-Volume Curves
Middle Aged
Pulmonary Ventilation / drug effects*
Vital Capacity
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A study of co-positivity of three multipuncture techniques with intradermal PPD tuberculin.
Next Document:  The role of hyperventilation in exercise-induced bronchoconstriction.