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Responses to Exercise Differ For Chronic Fatigue Syndrome Patients with Fibromyalgia.
MedLine Citation:
PMID:  22157881     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are chronic multisymptom illnesses with substantial clinical and diagnostic overlap. We have previously shown that when controlling for aerobic fitness and accounting for comorbid FM, CFS patients do not exhibit abnormal cardiorespiratory responses during maximal aerobic exercise compared to healthy controls, despite differences in pain and exertion. PURPOSE: The purpose of the present study was to examine cardiac and perceptual responses to steady-state, submaximal exercise in CFS patients and healthy controls. METHODS: Twenty-one CFS patients [13 CFS with comorbid FM (CFS+FM)] and 14 controls completed 20 minutes of submaximal cycling exercise. Impedance cardiography was used to determine cardiac responses during exercise. Systolic blood pressure (SBP), perceived exertion (RPE) and leg-muscle pain were also measured. Data were analyzed using a doubly-multivariate, repeated-measures MANOVA to model the exercise response. RESULTS: There was a significant multivariate Time by Group interaction (p < 0.05). The CFS+FM group exhibited an exercise response characterized by higher stoke index, ventilatory equivalents for oxygen and carbon dioxide and RPE, lower SBP and similar HR responses. CONCLUSIONS: The present results extend upon our previous work with maximal exercise and show that CFS and CFS+FM differ in their responses to steady-state exercise. These resultshighlight the importance of accounting for comorbid conditions when conducting CFS research, particularly when examining psychophysiological responses to exercise.
Authors:
Dane B Cook; Aaron J Stegner; Paul R Nagelkirk; Jacob D Meyer; Fumiharu Togo; Benjamin H Natelson
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-12
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  -     ISSN:  1530-0315     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Department of Kinesiology, University of Wisconsin - Madison 2Research Service, William S. Middleton Memorial Veterans Hospital 3School of Physical Education, Sport & Exercise Science, Ball State University 4Graduate School of Education, The University of Tokyo 5Pain and Fatigue Study Center, Beth Israel Medical Center.
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