Document Detail


Responses of neurons in lateral parabrachial nucleus to antidromic stimulation of subfornical organ and to orthodromic stimulation of nucleus tractus solitarius in the rat
MedLine Citation:
PMID:  1788557     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Single unit discharges were extracellularly recorded from the neurons in the lateral parabrachial nucleus (LPBN) and responses of the recorded units to antidromic stimulation of the subfornical organ (SFO) and to orthodromic stimulation of the nucleus tractus solitarius (NTS) were observed in urethane-anesthetized rats. Following electrical stimulation of the SFO, 9.9% (51/151) of the LPBN units were antidromically activated. After activation of peripheral baroreceptors by raising arterial blood pressure with an intravenous injection of phenylephrine, 40.7% (22/54) of the LPBN units were inhibited and 27.8% (17/54) excited. Following orthodromic stimulation of the depressor area in the NTS, 55.6% (94/169) of the LPBN units showed an increase and 22.5% (38/169) a decrease in firing rates. Among the LPBN neurons antidromically activated by SFO stimulation, 2 units were inhibited by phenylephrine administrated i.v.; of the 8 units tested, when the NTS was stimulated, 6 were excited and 2 inhibited. The results suggest that the LPBN neurons may receive inhibitory or excitatory baroreceptive inputs from the NTS and then relay it directly to SFO.
Authors:
K Q Sun; G B Gu; Z S Han; G Ju
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Sheng li xue bao : [Acta physiologica Sinica]     Volume:  43     ISSN:  0371-0874     ISO Abbreviation:  Sheng Li Xue Bao     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1992-03-24     Completed Date:  1992-03-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  20730130R     Medline TA:  Sheng Li Xue Bao     Country:  CHINA    
Other Details:
Languages:  chi     Pagination:  213-9     Citation Subset:  IM    
Affiliation:
Department of Physiology, Shanxi Academy of Traditional Chinese Medicine.
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MeSH Terms
Descriptor/Qualifier:
Animals
Electric Stimulation
Electrophysiology
Male
Medulla Oblongata / physiology*
Neurons / physiology*
Phenylephrine / pharmacology
Preoptic Area / physiology
Pressoreceptors / physiology
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
59-42-7/Phenylephrine

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