Document Detail

Responses of natural wildlife populations to air pollution.
MedLine Citation:
PMID:  7381962     Owner:  NLM     Status:  MEDLINE    
Deer mice (Peromyscus californicus) trapped in areas of Los Angeles with high ambient air pollution are significantly more resistant to ozone (6.6 ppm for 12 h) than are mice trapped from areas with low ambient pollution (56 versus 0% survival, respectively). Laboratory-born progeny of these mice show similar response patterns, indicating a genetic basis to this resistance. Young mice (less than 1 yr of age) are more sensitive than older mice (15 versus 44% survival, respectively). Sensitivity is also affected by degree of inbreeding; progeny of full-sib crosses are more sensitive than randomly bred deer mice. The data suggest that deer mice are more resistant to ozone toxicity than are commercially bred laboratory mice and rats.
K E Richkind; A D Hacker
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of toxicology and environmental health     Volume:  6     ISSN:  0098-4108     ISO Abbreviation:  J Toxicol Environ Health     Publication Date:  1980 Jan 
Date Detail:
Created Date:  1980-08-15     Completed Date:  1980-08-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513622     Medline TA:  J Toxicol Environ Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  IM    
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MeSH Terms
Air Pollution*
Animals, Wild / physiology
Nitrogen Dioxide / toxicity
Ozone / toxicity
Peromyscus / physiology*
Reg. No./Substance:
10028-15-6/Ozone; 10102-44-0/Nitrogen Dioxide

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