Document Detail


Response variations of neurons in the lateral geniculate body of the freely moving rat.
MedLine Citation:
PMID:  7424597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The influence of the motivational state on the discharge rate and flash evoked activity of 57 single units of the dorsal lateral geniculate body (LGB) was investigated using extracellular microelectrodes. Flashes were presented either alone (control group) or followed by water reinforcement (trained group). With decreasing thirst motivation the background activity of most of the cells of both groups changed. This change consisted mainly in a decrease of the discharge rate. After satiation two thirds of the cells exhibited response variations to light stimuli. In trained thirsty animals in 10 out of 19 cells these changes were of very high degree, as the usual response pattern consisting in a sequence of excitatory and inhibitory phases was lost. Under such conditions the light acted as a conditioned stimulus in the thirsty animal. Nonvisual stimuli preceding the flashes and evoking inhibiton of the reflex behavior in trained rats produced small response modulations in about two thirds of the cells of either animal group. The assumption is made that the motivational state of the animal or environmental stimuli not belonging to the original conditioned stimulus - unconditioned stimulus (CS-US) paradigm are less effective in producing response changes of cells to physically equal stimuli than the biological relevance of the stimulus.
Authors:
D Albrecht; H Davidowa; H J Gabriel; A K Malikowa; W Rüdiger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurobiologiae experimentalis     Volume:  40     ISSN:  0065-1400     ISO Abbreviation:  Acta Neurobiol Exp (Wars)     Publication Date:  1980  
Date Detail:
Created Date:  1980-12-18     Completed Date:  1980-12-18     Revised Date:  2011-01-07    
Medline Journal Info:
Nlm Unique ID:  1246675     Medline TA:  Acta Neurobiol Exp (Wars)     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  463-78     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Conditioning, Classical / physiology*
Geniculate Bodies / cytology*
Light
Motivation / physiology
Rats
Satiety Response / physiology
Sensory Receptor Cells / physiology*
Thirst / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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