Document Detail

Response to programmed ventricular stimulation: sensitivity, specificity and relation to heart disease.
MedLine Citation:
PMID:  7113929     Owner:  NLM     Status:  MEDLINE    
This prospective study of 100 patients evaluated the sensitivity and specificity of the repetitive ventricular response and ventricular tachycardia induced by programmed electrical stimulation for identifying patients with spontaneous ventricular tachyarrhythmias. The influence of underlying heart disease on such sensitivity and specificity was also evaluated. The repetitive ventricular response was sensitive (92 percent) for detecting patients with prior spontaneous ventricular tachyarrhythmias, but lacked specificity (57 percent); the rate of false positive responses was 43 percent. Inducible ventricular tachycardia was less sensitive (65 percent) but more specific (98 percent); the rate of false positive responses was only 3 percent. Among the 100 patients, 71 had heart disease, 29 did not. The presence of underlying heart disease had no significant effect on the sensitivity and specificity of repetitive ventricular responses or ventricular tachycardia induced by programmed stimulation; it did not increase the rate of false positive responses. It is concluded that (1) ventricular tachycardia induced with programmed ventricular stimulation is an excellent basis for guiding the management of clinically significant ventricular tachyarrhythmias, regardless of underlying heart disease; and (2) the repetitive ventricular response is not useful for this purpose because of its high rate of false positive responses among patients with or without significant heart disease.
F D Livelli; J T Bigger; J A Reiffel; E S Gang; J N Patton; P M Noethling; L M Rolnitzky; J I Gliklich
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  50     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-10-12     Completed Date:  1982-10-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  452-8     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiac Pacing, Artificial*
Evaluation Studies as Topic
False Positive Reactions
Heart Diseases / diagnosis*,  physiopathology
Heart Ventricles / physiopathology*
Middle Aged
Prospective Studies
Tachycardia / physiopathology
Ventricular Function
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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