Document Detail

Response to paclitaxel and carboplatin in metastatic salivary gland cancer: a case report.
MedLine Citation:
PMID:  11933184     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Malignant tumors of the salivary gland are rare entities that are treated primarily by surgical resection. For patients with recurrent or unresectable disease, options include radiation therapy or chemotherapy; however, responses are few and of short duration. Patients with metastatic disease have been treated with chemotherapy, but, again, response rates have been low and of short duration. METHODS: A 52-year-old man was seen with a mass on his tongue. A biopsy revealed adenocarcinoma of a minor salivary gland. Ten months after surgical resection, neck dissection, and radiation therapy, the patient was found to have metastatic disease to the lung. Chemotherapy was initiated with carboplatin and paclitaxel. RESULTS: The patient obtained a complete response after six cycles of carboplatin and paclitaxel. CONCLUSIONS: The use of carboplatin and paclitaxel in the setting of metastatic salivary gland cancer is a viable option.
Janet C Ruzich; Marlyn C Ciesla; Joseph I Clark
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  24     ISSN:  1043-3074     ISO Abbreviation:  Head Neck     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-04     Completed Date:  2002-05-02     Revised Date:  2006-10-05    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  406-10     Citation Subset:  IM    
Copyright Information:
Copyright 2002 Wiley Periodicals, Inc.
Hematology and Oncology, Cardinal Bernadin Cancer Center, Loyola University Medical Center, 2160 South First Avenue, Maywood, Illinois, USA.
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MeSH Terms
Adenocarcinoma / drug therapy*,  secondary
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Carboplatin / therapeutic use*
Middle Aged
Paclitaxel / therapeutic use*
Salivary Gland Neoplasms / drug therapy*,  secondary
Treatment Outcome
Reg. No./Substance:
33069-62-4/Paclitaxel; 41575-94-4/Carboplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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