Document Detail


Response to hepatitis A vaccine in HIV patients in the HAART era.
MedLine Citation:
PMID:  16184045     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated the development of hepatitis A antibody after vaccination in a large cohort of patients studied in a clinical setting after the introduction of HAART. Overall, 130 of 214 vaccinated individuals developed hepatitis A antibody. In a multivariate analysis, only the CD4 cell count at the time of vaccination was associated with an absence of response. The lack of association with the nadir CD4 cell count suggests that patients will respond to vaccine after immunological reconstitution in response to HAART.
Authors:
David Rimland; Jodie L Guest
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AIDS (London, England)     Volume:  19     ISSN:  0269-9370     ISO Abbreviation:  AIDS     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-26     Completed Date:  2006-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  1702-4     Citation Subset:  IM; X    
Affiliation:
VA Medical Center and Emory University School of Medicine, Atlanta, GA, USA.
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MeSH Terms
Descriptor/Qualifier:
Antiretroviral Therapy, Highly Active*
CD4 Lymphocyte Count
HIV Infections / drug therapy*,  immunology
Hepatitis A Antibodies / biosynthesis*
Hepatitis A Vaccines / immunology*
Humans
Prospective Studies
Chemical
Reg. No./Substance:
0/Hepatitis A Antibodies; 0/Hepatitis A Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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