Document Detail

Response of the rat cardiovascular system to a moderate altitude in connection with endurance training.
MedLine Citation:
PMID:  3161099     Owner:  NLM     Status:  MEDLINE    
The authors investigated whether an altitude of 1,350 m would affect the rat cardiovascular system in the same way as genuine altitude hypoxia and the way it would take effect when combined with endurance training in the form of swimming It was found that 8 weeks spent at this altitude led to an increase in absolute and relative heart weight, to right ventricular hypertrophy, and to increased resistance of the myocardium to acute anoxia. Physical training at a moderate altitude resulted in an increase in the relative weight of the musculature of both the right and the left ventricle and of the septum. Unlike low altitude training, however, growth of the two compartments of the heart was proportional. The resistance of the myocardium of trained animals against anoxia was the same, irrespective of whether they trained at a low or a high altitude. The results show that even a moderate altitude is not a matter of indifference for the rat organism, but that it leads to characteristic manifestations of altitude hypoxia in the cardiovascular system.
E Barta; B Ostádal; V Pelouch; J Procházka; V Strec
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Physiologia Bohemoslovaca     Volume:  34     ISSN:  0369-9463     ISO Abbreviation:  Physiol Bohemoslov     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-28     Completed Date:  1985-08-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0175317     Medline TA:  Physiol Bohemoslov     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  103-10     Citation Subset:  IM; S    
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MeSH Terms
Anoxia / physiopathology*
Cardiovascular System / physiopathology*
Physical Conditioning, Animal*
Rats, Inbred Strains

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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