Document Detail


Response of psoriatic nails to oral photochemotherapy.
MedLine Citation:
PMID:  7416754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ten patients with generalized psoriasis, which included nail involvement, were treated with total-body oral photochemotherapy. A combination of methoxsalen and high-intensity ultraviolet A radiation was employed and its therapeutic efficacy in nail psoriasis ascertained. Among the ten patients, there were 26 instances of the following nail signs: pitting, onycholysis, "oil drop" change, subungual hyperkeratosis, nail-plate crumbling, proximal nail-fold psoriasis, and onychorrhexis. Of the 26, eighteen improved by 50% or more. Only pitting failed to respond to therapy in all of the eight patients who had this change.
Authors:
J L Marx; R K Scher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  116     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1980-11-25     Completed Date:  1980-11-25     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1023-24     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Methoxsalen / administration & dosage,  therapeutic use*
Nail Diseases / drug therapy*
Photochemotherapy*
Psoriasis / drug therapy*
Ultraviolet Rays
Chemical
Reg. No./Substance:
298-81-7/Methoxsalen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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