| Response of postpsychotic depression to adjunctive imipramine or amitriptyline. | |
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MedLine Citation:
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PMID: 6131064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Case histories were reviewed of 25 patients with RDC diagnoses of schizophrenia or schizoaffective disorder who developed a clinical syndrome of depression subsequent to the resolution of their psychotic episodes. Of these patients, 14 were then treated with imipramine and 11 with amitriptyline in addition to their neuroleptic drugs. As a group, the patients did well--48% had a remission of depressive symptoms and an additional 32% improved. Psychotic exacerbation was noted in only one patient. Imipramine seemed more beneficial than amitriptyline in these patients. |
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Authors:
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S G Siris; A E Rifkin; G T Reardon |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of clinical psychiatry Volume: 43 ISSN: 0160-6689 ISO Abbreviation: J Clin Psychiatry Publication Date: 1982 Dec |
Date Detail:
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Created Date: 1983-04-07 Completed Date: 1983-04-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7801243 Medline TA: J Clin Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 485-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ambulatory Care Amitriptyline / therapeutic use* Antipsychotic Agents / therapeutic use Depressive Disorder / drug therapy*, etiology Drug Therapy, Combination Female Humans Imipramine / therapeutic use* Male Middle Aged Psychotic Disorders / drug therapy Schizophrenia / complications*, drug therapy Schizophrenic Psychology |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 50-48-6/Amitriptyline; 50-49-7/Imipramine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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