Document Detail


Response of monkey glabrous skin mechanoreceptors to random noise sequences: II. Dynamic stimulus state analysis.
MedLine Citation:
PMID:  8725645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The responses of monkey glabrous skin slowly adapting (SAI, Merkel cell), rapidly adapting (RA, Meissner) and Pacinian corpuscle (PC) mechanoreceptors were analyzed as a function of the instantaneous position, velocity, and acceleration of a dynamic stimulus. For these experiments, a vibrotactile punctate stimulator was driven by a non-repeating-noise sequence. The resulting data (sampled stimulus waveform, windowed impulse) were processed in several ways. Initially, input-output correlation analysis was implemented to generate spike-aligned averages of the stimulus waveform preceding and following impulse initiation. From this analysis, it was determined that dual-responding RA and PC afferents--that is, those afferents that responded to both indenting and extracting stimulus movements--universally responded in a nearly perfectly symmetrical manner to the stimulus. Subsequently, two-dimensional (position, velocity) state histograms were generated and used to assess mechanoreceptor dynamic stimulus sensitivities. From these state histograms, it was determined that the threshold for impulse initiation by SAI afferents was preferentially sensitive to the indentation position of the stimulus, with only a minor sensitivity to stimulus velocity. RA afferent thresholds were sensitive to a continuum of dynamic stimulus velocities and positions. At the extremes, RA afferent impulses could be initiated by either a highly indented, low-velocity stimulus or high-velocity stimulus with a limited indentation position. PC afferents appeared to be preferentially sensitive to a combination of stimulus velocity and acceleration, but the data-sampling interval was too coarse to adequately resolve the full range of dynamic stimulus sensitivities.
Authors:
F J Looft
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Somatosensory & motor research     Volume:  13     ISSN:  0899-0220     ISO Abbreviation:  Somatosens Mot Res     Publication Date:  1996  
Date Detail:
Created Date:  1996-11-06     Completed Date:  1996-11-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904127     Medline TA:  Somatosens Mot Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  11-28     Citation Subset:  IM; S    
Affiliation:
Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts 01609, USA. fjlooft@ee.wpi.edu
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MeSH Terms
Descriptor/Qualifier:
Afferent Pathways / physiology
Animals
Attention / physiology*
Macaca mulatta
Mechanoreceptors / physiology*
Median Nerve / physiology
Merkel Cells / physiology
Models, Neurological
Orientation / physiology*
Pacinian Corpuscles / physiology
Regression Analysis
Sensory Thresholds / physiology
Signal Processing, Computer-Assisted
Skin / innervation*
Touch / physiology*
Ulnar Nerve / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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