Document Detail


Response inhibition deficits in obsessive-compulsive disorder.
MedLine Citation:
PMID:  12057828     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Difficulty inhibiting irrelevant information may play a central role in the aetiology of obsessive-compulsive disorder (OCD). The aim of the present study was to determine whether OCD subjects (n=20) exhibit deficits in behavioural and cognitive inhibition compared with a clinical control group diagnosed with panic disorder (n=20). All subjects were administered a Go/Nogo task (a measure of behavioural inhibition) and a Stroop test (a measure of cognitive inhibition). OCD subjects made more commission errors on the Go/Nogo task, and they made more errors and displayed longer reaction times on the interference trial of the Stroop task. Trends towards correlations were observed between OCD severity scores and Stroop reaction time, where the more severe the OCD symptoms the faster was the response. No correlations between clinical symptomatology or subject demographics and the Go/Nogo task were observed. It was demonstrated that OCD subjects exhibit deficits in behavioural and cognitive inhibition, which together may underlie the repetitive symptomatic behaviours of the disorder, such as compulsions and obsessions.
Authors:
Shelley Bannon; Craig J Gonsalvez; Rodney J Croft; Philip M Boyce
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychiatry research     Volume:  110     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-11     Completed Date:  2002-08-20     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  165-74     Citation Subset:  IM    
Affiliation:
Department of Psychology, University of Wollongong, Australia. shelley@app-practice.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Female
Humans
Inhibition (Psychology)*
Male
Middle Aged
Obsessive-Compulsive Disorder / diagnosis*
Reaction Time
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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