Document Detail

Response inhibition deficits in obsessive-compulsive disorder.
MedLine Citation:
PMID:  12057828     Owner:  NLM     Status:  MEDLINE    
Difficulty inhibiting irrelevant information may play a central role in the aetiology of obsessive-compulsive disorder (OCD). The aim of the present study was to determine whether OCD subjects (n=20) exhibit deficits in behavioural and cognitive inhibition compared with a clinical control group diagnosed with panic disorder (n=20). All subjects were administered a Go/Nogo task (a measure of behavioural inhibition) and a Stroop test (a measure of cognitive inhibition). OCD subjects made more commission errors on the Go/Nogo task, and they made more errors and displayed longer reaction times on the interference trial of the Stroop task. Trends towards correlations were observed between OCD severity scores and Stroop reaction time, where the more severe the OCD symptoms the faster was the response. No correlations between clinical symptomatology or subject demographics and the Go/Nogo task were observed. It was demonstrated that OCD subjects exhibit deficits in behavioural and cognitive inhibition, which together may underlie the repetitive symptomatic behaviours of the disorder, such as compulsions and obsessions.
Shelley Bannon; Craig J Gonsalvez; Rodney J Croft; Philip M Boyce
Related Documents :
21786898 - The effect of lip-reading on primary stream segregation.
21728468 - Selective attention and distractor frequency in naming performance: comment on dhooge a...
19962128 - Valence of autobiographical memories: the role of mood, cognitive reappraisal, and supp...
18775088 - Memory impairment in young women at increased risk of depression: influence of cortisol...
22232688 - A morphologically specialized soldier caste improves colony defense in a neotropical eu...
21441218 - Are we puppets on a string? comparing the impact of contingency and validity on implici...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychiatry research     Volume:  110     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-11     Completed Date:  2002-08-20     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  165-74     Citation Subset:  IM    
Department of Psychology, University of Wollongong, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Inhibition (Psychology)*
Middle Aged
Obsessive-Compulsive Disorder / diagnosis*
Reaction Time
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Executive function deficits associated with symptoms of schizotypy and obsessive-compulsive disorder...
Next Document:  The Stereotypy Rating Inventory for frontotemporal lobar degeneration.