Document Detail

Response of growth and fatty acid compositions of Nannochloropsis sp. to environmental factors under elevated CO2 concentration.
MedLine Citation:
PMID:  16791719     Owner:  NLM     Status:  MEDLINE    
Nannochloropsis sp. was grown with different levels of nitrate, phosphate, salinity and temperature with CO(2) at 2,800 microl l(-1). Increased levels of NaNO(3) and KH(2)PO(4) raised protein and polyunsaturated fatty acids (PUFAs) contents but decreased carbohydrate, total lipid and total fatty acids (TFA) contents. Nannochloropsis sp. grew well at salinities from 22 to 49 g l(-1), and lowering salinity enhanced TFA and PUFAs contents. TFA contents increased with the increasing temperature but PUFAs contents decreased. The highest eicosapentaenoic acid (EPA, 20:5 omega3) content based on the dry mass was above 3% under low N (150 microM NaNO(3)) or high N (3000 microM NaNO(3)) condition. Excessive nitrate, low salinity and temperature are thus favorable factors for improving EPA yields in Nannochloropsis sp.
Hanhua Hu; Kunshan Gao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-06-22
Journal Detail:
Title:  Biotechnology letters     Volume:  28     ISSN:  0141-5492     ISO Abbreviation:  Biotechnol. Lett.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-04     Completed Date:  2007-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008051     Medline TA:  Biotechnol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  987-92     Citation Subset:  IM    
State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan 430072, PR China.
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MeSH Terms
Algae / physiology*
Bioreactors / microbiology*
Carbon Dioxide / administration & dosage*
Cell Culture Techniques / methods*
Cell Proliferation / drug effects
Dose-Response Relationship, Drug
Eicosapentaenoic Acid / metabolism*
Nitrates / metabolism*
Phosphates / metabolism*
Sodium Chloride / metabolism
Reg. No./Substance:
0/Nitrates; 0/Phosphates; 124-38-9/Carbon Dioxide; 1553-41-9/Eicosapentaenoic Acid; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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