Document Detail


Response of Halomonas campisalis to saline stress: changes in growth kinetics, compatible solute production and membrane phospholipid fatty acid composition.
MedLine Citation:
PMID:  17651393     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The haloalkaliphile Halomonas campisalis, isolated near Soap Lake, Washington, was grown under both aerobic and denitrifying conditions from 0 to 260 g L(-1) NaCl, with optimal growth occurring at 20 and 30 g L(-1) NaCl, respectively. Halomonas campisalis was observed to produce high concentrations of compatible solutes, most notably ectoine (up to 500 mM within the cytoplasm), but hydroxyectoine and glycine betaine were also detected. The types and amounts of compatible solutes produced depended on salinity and specific growth rate, as well as on the terminal electron acceptor available (O(2) or NO(3) (-)). A decrease in ectoine production was observed with NO(3) (-) as compared with O(2) as the terminal electron acceptor. In addition, changes in the phospholipid fatty acid composition were measured with changing salinity. An increase in trans fatty acids was observed in the absence of salinity, and may be a response to membrane instability. Cyclic fatty acids were also observed to increase, both in the absence of salinity, and at very high salinities, indicating cell stress at these conditions.
Authors:
John E Aston; Brent M Peyton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2007-07-25
Journal Detail:
Title:  FEMS microbiology letters     Volume:  274     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-16     Completed Date:  2008-07-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  196-203     Citation Subset:  IM    
Affiliation:
Department of Chemical and Biological Engineering, Montana State University, Bozeman, MT, USA.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids, Diamino / metabolism
Cell Membrane / chemistry,  drug effects*,  physiology
Fatty Acids / biosynthesis
Halomonas / genetics,  growth & development*,  physiology*
Kinetics
Osmosis / physiology
Phospholipids / biosynthesis
Sodium Chloride / pharmacology*
Solutions / metabolism
Solvents
Chemical
Reg. No./Substance:
0/Amino Acids, Diamino; 0/Fatty Acids; 0/Phospholipids; 0/Solutions; 0/Solvents; 7647-14-5/Sodium Chloride; 96702-03-3/ectoine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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