Document Detail


Respiratory viruses in bronchiolitis and their link to recurrent wheezing and asthma.
MedLine Citation:
PMID:  19892232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bronchiolitis is the leading cause of hospitalization for children younger than 1 year of age and these hospitalized children have an increased risk for developing childhood asthma. It remains unclear, however, which children who have severe bronchiolitis (eg, an episode requiring hospitalization) will develop recurrent wheezing or asthma. Although many environmental and genetic factors may play a role in the pathway from bronchiolitis to asthma, this article focuses on the viruses that have been linked to bronchiolitis and how these viruses may predict or contribute to future wheezing and asthma. The article also discusses vitamin D as an emerging risk factor for respiratory infections and wheezing.
Authors:
Jonathan M Mansbach; Carlos A Camargo
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinics in laboratory medicine     Volume:  29     ISSN:  1557-9832     ISO Abbreviation:  Clin. Lab. Med.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-06     Completed Date:  2010-02-09     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  8100174     Medline TA:  Clin Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  741-55     Citation Subset:  IM    
Affiliation:
Department of Medicine, Children's Hospital Boston, Harvard Medical School, Main Clinical Building 9 South, #9157, Boston, MA 02115, USA. jonathan.mansbach@childrens.harvard.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Asthma / epidemiology,  virology*
Bronchiolitis, Viral / complications*,  epidemiology
Child
Child, Preschool
Humans
Infant
Respiratory Sounds / etiology*
Risk Factors
Vitamin D Deficiency / complications
Grant Support
ID/Acronym/Agency:
K23 AI-77801/AI/NIAID NIH HHS; K23 AI077801-01A1/AI/NIAID NIH HHS; U01 AI-67693/AI/NIAID NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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