Document Detail


Respiratory variations in the photoplethysmographic waveform: acute hypovolaemia during spontaneous breathing is not detected.
MedLine Citation:
PMID:  20530847     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent studies using photoplethysmographic (PPG) signals from pulse oximeters have shown potential to assess hypovolaemia during spontaneous breathing. This signal is heavily filtered and reports are based on respiratory variations in the small pulse synchronous variation of PPG. There are stronger respiratory variations such as respiratory synchronous variation (PPGr) in the baseline of the unfiltered PPG signal. We hypothesized that PPGr would increase during hypovolaemia during spontaneous breathing. Hemodynamic and respiratory data were recorded together with PPG infrared signals from the finger, ear and forearm from 12 healthy male volunteers, at rest and during hypovolaemia created by the application of a lower body negative pressure (LBNP) of 15, 30 and 60 cmH(2)O. Hemodynamic and respiratory values changed significantly. From rest to the LBNP of 60 cmH(2)O systolic blood pressure fell from median (IQR) 116 (16) to 101 (23) mmHg, the heart rate increased from 58 (16) to 73 (16) beats min(-1), and the respiratory rate increased from 9.5 (2.0) to 11.5 (4.0) breaths min(-1). The amplitude of PPGr did not change significantly at any measurement site. The strongest effect was seen at the ear, where the LBNP of 60 cmH(2)O gave an amplitude increase from 1.0 (0.0) to 1.31 (2.24) AU. PPG baseline respiratory variations cannot be used for detecting hypovolaemia in spontaneously breathing subjects.
Authors:
Lena Nilsson; Tomas Goscinski; Marcus Lindenberger; Toste Länne; Anders Johansson
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Publication Detail:
Type:  Journal Article     Date:  2010-06-07
Journal Detail:
Title:  Physiological measurement     Volume:  31     ISSN:  1361-6579     ISO Abbreviation:  Physiol Meas     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-29     Completed Date:  2010-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  England    
Other Details:
Languages:  eng     Pagination:  953-62     Citation Subset:  IM    
Affiliation:
Division of Drug Research, Department of Medical and Health Sciences, Linköping University, S 581 83 Linköping, Sweden. lena.nilsson@lio.se
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Humans
Hypovolemia / diagnosis*,  physiopathology*
Lower Body Negative Pressure
Male
Photoplethysmography / instrumentation*
Respiration*
Signal Processing, Computer-Assisted
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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