Document Detail


Respiratory sinus arrhythmia: why does the heartbeat synchronize with respiratory rhythm?
MedLine Citation:
PMID:  14769752     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Respiratory sinus arrhythmia (RSA) is heart rate variability in synchrony with respiration, by which the R-R interval on an ECG is shortened during inspiration and prolonged during expiration. Although RSA has been used as an index of cardiac vagal function, it is also a physiologic phenomenon reflecting respiratory-circulatory interactions universally observed among vertebrates. Previous studies have shown that the efficiency of pulmonary gas exchange is improved by RSA, suggesting that RSA may play an active physiologic role. The matched timing of alveolar ventilation and its perfusion with RSA within each respiratory cycle could save energy expenditure by suppressing unnecessary heartbeats during expiration and ineffective ventilation during the ebb of perfusion. Furthermore, evidence has accumulated of a possible dissociation between RSA and vagal control of that heart rate, suggesting differential controls between the respiratory modulation of cardiac vagal outflow and cardiac vagal tone. RSA or heart rate variability in synchrony with respiration is a biological phenomenon, which may have a positive influence on gas exchange at the level of the lung via efficient ventilation/perfusion matching.
Authors:
Fumihiko Yasuma; Jun-Ichiro Hayano
Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Chest     Volume:  125     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-10     Completed Date:  2004-03-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  683-90     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Suzuka National Hospital, 3-2-1 Kasado, Suzuka 513-8501, Japan. f-yasuma@mtb.biglobe.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Arrhythmia, Sinus / physiopathology*
Autonomic Nervous System / physiology
Cardiovascular Physiological Phenomena
Female
Heart Rate / physiology
Humans
Male
Middle Aged
Pulmonary Circulation
Pulmonary Gas Exchange
Respiration*
Respiratory Mechanics
Respiratory Physiological Phenomena*
Sensitivity and Specificity
Vagus Nerve / physiology*
Comments/Corrections
Comment In:
Chest. 2004 Oct;126(4):1385-6; author reply 1386-7   [PMID:  15486413 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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