Document Detail


Respiratory-related evoked potential measurements using high-density electroencephalography.
MedLine Citation:
PMID:  21067971     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The respiratory-related evoked potential (RREP) has become an established technique for studying the neural processing of respiratory signals. However, the increasing availability of high-density EEG systems necessitates new criteria for obtaining acceptable RREPs with these systems.
METHODS: The present study examined the minimum criteria for the number of inspiratory occlusions that need to be averaged in order to obtain a signal-to-noise ratio of 2:1 (3 dB) for the RREP components Nf, P1, N1, P2 and P3 with a 129 sensor high-density EEG system in 12 healthy volunteers. RREPs resulting from averaging 8, 16, 32 and 64 inspiratory occlusions were compared.
RESULTS: Analyses of signal-to-noise ratios demonstrated that a minimum of 32 and 16 inspiratory occlusions should be averaged for Nf and P1, respectively. For N1, P2, and P3, an average of at least 8 inspiratory occlusions is required. However, to account for inter-individual variability, 64 averaged occlusions for Nf, 32 averaged occlusions for P1, and 16 averaged occlusions for N1, P2, and P3 are recommended which more reliably exceed the signal-to-noise threshold.
CONCLUSIONS: These numbers provide the minimum and the recommended criteria for reliable measurements of the RREP for an adequate number of repeated occlusion epochs to be averaged in order to yield a reliable signal-to-noise ratio using a 129 sensor EEG system.
SIGNIFICANCE: The present study provides minimum and recommended criteria for obtaining acceptable RREPs with high-density EEG systems.
Authors:
Andreas von Leupoldt; Andreas Keil; Paul W Davenport
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-11-09
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  122     ISSN:  1872-8952     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-09     Completed Date:  2011-05-17     Revised Date:  2012-04-04    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  815-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Physiological Sciences, University of Florida, Gainesville, USA. andreas.vonleupoldt@uni-hamburg.de
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MeSH Terms
Descriptor/Qualifier:
Data Interpretation, Statistical
Electroencephalography / methods*,  statistics & numerical data
Evoked Potentials / physiology*
Female
Humans
Male
Reproducibility of Results
Respiratory Mechanics / physiology*
Young Adult
Grant Support
ID/Acronym/Agency:
P50 MH 72850/MH/NIMH NIH HHS; P50 MH072850-05/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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