Document Detail


Respiratory muscle strength and hemodynamics in chronic heart failure.
MedLine Citation:
PMID:  8306727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To examine whether respiratory muscle weakness is associated with cardiac function and/or exercise capacity in chronic heart failure (CHF), 23 patients with CHF were evaluated with respiratory muscle strength, pulmonary function tests, cardiac catheterization, and exercise test. The subjects were divided into three groups on their New York Heart Association (NYHA) functional class. Group A consisted of 13 patients with NYHA functional classification class 3 or 4, group B consisted of 10 patients with NYHA classification class 2, and group C consisted of 15 age-matched normal controls. Respiratory muscle strength was assessed with maximal static inspiratory mouth pressure at residual volume level and expiratory mouth pressure at total lung capacity level (PImax, PEmax, respectively). Pulmonary functions in patients with CHF showed almost normal. PImax in group A was significantly less than that in group B or C, although PImax in group B was not significantly different from that in group C. In the patients with CHF, PImax correlated positively with cardiac index and maximal oxygen consumption (r = 0.460 and r = 0.503, p < 0.05, respectively). These findings suggest that inspiratory muscle strength, which was impaired in patients with severe CHF, may be dependent on cardiac function and may be one of the limiting factors on impaired exercise capacity in the patients with CHF.
Authors:
Y Nishimura; H Maeda; K Tanaka; H Nakamura; Y Hashimoto; M Yokoyama
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chest     Volume:  105     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-03-17     Completed Date:  1994-03-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-9     Citation Subset:  AIM; IM    
Affiliation:
First Department of Internal Medicine, Kobe University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Blood Pressure / physiology
Cardiac Output / physiology
Exercise Tolerance / physiology*
Female
Forced Expiratory Volume / physiology
Heart / physiopathology*
Heart Failure / physiopathology*
Hemodynamics / physiology
Humans
Inhalation / physiology
Male
Maximal Expiratory Flow Rate / physiology
Middle Aged
Muscle Contraction / physiology
Pressure
Pulmonary Ventilation / physiology
Pulmonary Wedge Pressure / physiology
Residual Volume / physiology
Respiratory Muscles / physiopathology*
Total Lung Capacity / physiology
Vital Capacity / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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